biosplice therapeutics ipo
Clinical Project Manager at Biosplice Therapeutics San Diego County, California, United States. Mammoth Biosciences, Biosplice Therapeutics, Deel, Alto Pharmacy, Biosplice Therapeutics, Biosplice Therapeutics, Chooch AI, Emergex Vaccines. In September 2020, Sorrento Therapeutics released positive Phase 1b trial data (clinicaltrials.gov NCT03542838) of resiniferatoxin (RTX) in the reduction of OsteoArthritis (OA) knee pain. Ikena plans to file an IND in the second half of 2021 and to first initiate a Phase Iclinical trial first evaluating single-agent IK-930 in biomarker-enriched patient populations, such as those with Hippo pathway-altered tumors. Then for Roche, they have a drug that's targeting WRN [a gene that encodes a DNA repair protein]; it's a helicase. In January, the company secured $120 million in a Series B financing round. Brian, are there any of these that you think investors should want to have on their radar? Our scientific platform is based on biological discoveries that govern tissue specialization and enable us to selectively eliminate harmful proteins using small molecules. Biosplice Therapeutics is developing tissue-level regeneration technologies that will be used in the fields of functional medicine and regenerative medicine. Its scientific platform is based on biological discoveries that govern tissue specialization and enable it to selectively eliminate harmful proteins using small molecules. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. Learn more at https://www.biosplice.com, Corporate Contact:Erich HorsleyBiosplice Therapeutics, Inc.erich.horsley@biosplice.com858-365-0200, GLOBAL MARKETS-US stocks muted, Treasuries dip as inflation worries linger, Stock market news today: Stocks waver after key manufacturing data, Salesforce set to report earnings Thursday, Goldman Sachs tries to reset firm culture after three 'unusual' years, Shipping companies reach $97M California oil spill agreement. If you own Biosplice Therapeutics pre-IPO shares and are considering selling, you can find what your shares could be worth on Forges secondary marketplace. Corporate Contact: Erich Horsley Biosplice Therapeutics, Inc. When he told a group of senior scientists about his ideas for drug delivery at a Chinese restaurant in 1979, one of them blew cigar smoke in his face. A biotech born out of the work of Stanford CAR-T leader Crystal Mackall is publicly unveiling its $200 million Series A Wednesday, after already going through a Phase I clinical trial, rebranding and setting up plans for a potential registrational study. Samumed made quite the entrance back in 2016, when it launched with some anti-aging programs and a whopping $12 billion valuation. By registering, you agree to Forges Terms of Use. Alto is a full-service pharmacy powered by a team of experts dedicated to making your doctor's orders their own. Each of these companies announced their intentions this week. Biosplices target class governs the selection of tissue-specific mRNA splice sites, making them attractive, druggable targets within the cellular command and control center. Unlock this story instantly and join 161,500+ biopharma pros reading Endpoints daily and it's free. The company focuses on potential treatments for several diseases; its osteoarthritis program is its most advanced. See our Risk Factors for a more detailed explanation of the risks involved by investing through EquityZens platform. Chief Financial Officer and Chief Business Officer of Biosplice Therapeutics, Inc. San Diego County, California, United States. Fulcrum Therapeutics Announces Clinical Hold on FTX-6058 in Sickle Cell Disease,CAMBRIDGE, Mass., Feb. 24, 2023 (GLOBE NEWSWIRE) -- Fulcrum Therapeutics, Inc. (Nasdaq: FULC), a clinical-stage biopharmaceutical company focused on. After reaching a $12 billion valuation in 2018, Biosplice appears to be falling back down to Earth, and its workforce is taking the brunt. Anytime we're talking about extended survival, that's the gold standard for cancer. Price as of February 28, 2023, 4:00 p.m. Bioscience & Technology Business CenterThe University of KansasLawrence, Kansas. SAN DIEGO, Jan. 27, 2022 /PRNewswire/ -- Biosplice Therapeutics, Inc., a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation for major diseases, and . 10 stocks we like better than Bristol Myers SquibbWhen our award-winning analyst team has a stock tip, it can pay to listen. Biosplice Therapeutics, Inc. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. (Biosplice), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. *Stock Advisor returns as of June 7, 2021. SAN DIEGO, Jan. 27, 2022 /PRNewswire/ -- Biosplice Therapeutics, Inc., a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation for major diseases, . And then if they knock out or block the activity of WRN, then the tumors can't repair those mutations that they're making, and then hopefully the tumor will just die. Edgewises lead drug candidate is EDG-5506, an orally administered small molecule designed to address the root cause of dystrophinopathies, in development for the treatment of Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy (DMD). EquityZen Securities LLC (EquityZen Securities) is a subsidiary of EquityZen Inc. EquityZen Securities is a broker/dealer registered with the Securities Exchange Commission and is a FINRA/SIPC member firm. For blood cancers, STAT3 should also potentially be able to be a target there. Vividion Therapeutics has filed to go public. Stemming from foundational discoveries in Wnt pathway. His research on drug delivery, which led him to co-found Moderna in 2010, went on to prove critical in developing the companys Covid-19 vaccine. In December, Edgewise raised $95 million in a Series C financing round. Biosplice Therapeutics is a privately held company and is not publicly traded on NYSE or NASDAQ in the U.S. To buy pre-IPO shares of a private company, you need to be an accredited investor. In human DNA, approximately 20,000 genes code for hundreds of thousands of distinct proteins required for normal tissue development and function. Biosplice Therapeutics, Inc. You can also learn more about how to sell your private shares before getting started. SAN DIEGO and CHENGDU, China, Sept. 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK . Equity securities are offered through EquityZen Securities. Biosplice Therapeutics is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule therapeutics based on the pioneering science of alternative pre-mRNA splicing. Copyright 2023 Forge Global, Inc. All rights reserved. The greatest drivers of growth in the global OA market include the launch of eight new pipeline therapies during the forecast period and a steadily climbing diagnosed prevalence in many . Viking accuses Chinese biotech of 'ruse' to raid trade secrets and make off with NASH cache. Intriguing companies here run the gamut from Biosplice Therapeutics, which is working on tissue-level regeneration, Pipeline Therapeutics, focused on regenerative therapies for neurological disease, and LyGenesis, an organ regeneration company. Alternative splicing is an essential biological mechanism that regulates the diversification of proteins in a cell, which, in turn, determines cell type and function. Eli Lilly is looking to get ahead of any more federal action on insulin prices, announcing today that it will not only slash its most commonly used insulin by 70%, but cap out-of-pocket costs for those on commercial insurance at $35 per month just as the federal government recently did for those insured by Medicare. Please note this link is one-time use only and is valid for only 24 hours. His research on drug delivery, which led him to co-found Moderna in 2010, went on to prove critical in developing the companys Covid-19 vaccine. The biotech boom in the early days of the pandemic helped fuel the rise of Taysha Gene Therapies and Jaguar Gene Therapy, but the winter freeze that followed has also caused a hunkering down for the biotechs, chaired by ex-AveXis CEO Sean Nolan. Internal digital and data science expertise is critical to developing a united value proposition that aligns the benefits of the digital and medicinal product. With their platform's origins in small molecule-based Wnt pathway modulation, they develop therapeutics to address a range of degenerative diseases, regenerative medicine, and oncology. Biosplice Therapeutics is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule therapeutics based on the pioneering science of alternative pre-mRNA splicing. 2/27/2023. This morning, two of those companies, Ikena Oncology andDesign Therapeutics, join Edgewise Therapeutics by trading on the exchange. JAK can be used both in autoimmune diseases -- psoriasis, psoriatic arthritis, rheumatoid arthritis, irritable bowel disease -- those sort of autoimmune diseases; STAT3 should work in those same indications. SAN DIEGO, Sept. 29, 2022 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation. Please note the magic link is Biosplice Therapeutics; Organogenesis Holdings; Techfields Pharma; Centrexion Therapeutics; Regeneron; Xalud Therapeutics; Bone Therapeutics; Key Highlights. As chief business officer and strategy chief for the Broad over a decade-long stretch, hed worked with all the big names in a scientific discipline that promises to upend the therapeutics field eventually. Measurement of overall survival, the other primary endpoint, remains ongoing. Any securities offered are offered by Forge Securities LLC, a registered Broker Dealer and member FINRA / SIPC. Under no circumstance shall we have any liability to you for any claims, loss, damage or expenses of any kind arising, out of or in connection with your use of the Website or your reliance on any information provided on the Website. The data in the tables and charts is based on data from public sources and although we make every effort to compile the data, it may not coincide with the actual data of the issuer. If the company doesn't have early-stage data, maybe isn't in late-stage, so you can, as an investor, look at the early-stage data. Biosplice Therapeutics (formerly Samumed) "Biosplice's mission is to restore health by delivering first-in-class therapies that harness alternative splicing.". Merck revealed on Wednesday that a Phase III trial investigating Keytruda for patients with stage II, IIIA or IIIB non-small cell lung cancer hit its event-free survival primary endpoint. You better start looking for another job, the scientist said. Below are the key stats of Biosplice Therapeutics patent prosecution at the USPTO. Our Private Market Specialists are available to answer any questions you might have and can help connect you with a buyer from our network of 125,000 accredited investors and institutions. Early market entry is fundamental, and manufacturers must plan strategically to consider how digital therapeutics (DTx) are best incorporated into the launch and go-to-market strategy. Catherine Stehman-Breen, Chroma Medicine CEO, David Ricks, Eli Lilly CEO (David Paul Morris/Bloomberg via Getty Images), Hemolytic Anemia Sales Specialist, Rare Genetic Diseases, Osman Kibar lays down his hand at Samumed, stepping away from CEO role as his once-heralded anti-aging biotech rebrands, Digital therapeutics: The key to maximizing the potential of medicinal assets, A radioactive prostate cancer therapy is a last lifeline for patients. We'll e-mail you a link to set a new password. The name Biosplice echoes our science much more than Samumed does.. Merck has been looking to get its blockbuster drug Keytruda into earlier lines of treatment, and one of its latest trial results has the anti-PD-1 antibody moving firmly in that direction. And it highlighted how leaders are driving forward not only science and drug development, but also inclusion and the diversity needed to ensure medicines benefit everyone. one-time use only and expires after 24 hours. Funds from that round, as well as the IPO, will be used to advance the companys muscular dystrophy program, as well as other indications. Still, he faced a string of rejected grants and skepticism. Your use of the Website and your reliance on any information on the Website is solely at your own risk. Both Moffitt Cancer Center and Mayo Clinic in Florida, not too far from Domingos and his family, said he would have to wait between three and a half and four months to get the treatment. Alfredo Naj Domingos prostate cancer was spreading. Biosplice Therapeutics, Inc. (formerly Samumed, LLC) is a private biopharmaceutical company based in San Diego, California.It was founded in 2008 by Osman Kibar.. Samumed's products in development target novel components of the Wnt signaling pathway. Samumed is in the medical research and development for tissue-level regeneration. Biosplice Therapeutics is a private company and not publicly traded. Stemming from foundational discoveries in Wnt pathway modulation, Biosplice has elucidated novel biology linking CLK/DYRK kinases to the therapeutic regulation of alternative splicing. magic link that lets you log in quickly without using a password. The company is headquartered in San Diego, California. 1985 - 2023 BioSpace.com. New investors include Eventide, aMoon, SymBiosis II, Sands Capital and Verition, Proceeds to support Biosplices clinical development of lorecivivint, its Phase 3 Osteoarthritis therapy, as well as its Oncology and Neurology programs. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA. Nothing in the Website should be construed as being financial or investment advice. Fate Therapeutics is a stem cell and developmental biology research company using biological mechanisms to develop stem cell therapeutics. The approval request includes both a BLA and NDA. Gerostate Alpha raising $500k through WeFunder (Live Now). Biosplice Therapeutics, Inc. erich.horsley@biosplice.com 858-365-0200. From delivering prescriptions to coordinating with insurance, digging for discounts, and answering, Alto works behind-the-scenes to remove any obstacles standing in the way of your care. Still, he faced a string of rejected grants and skepticism. Internal digital and data science expertise is critical to developing a united value proposition that aligns the benefits of the digital and medicinal product. That's in the same pathway as JAK, which we've talked about a lot. Carlsbad, Calif.-based Design Therapeutics begins trading on the Nasdaq under the ticker symbol DSGN. CARGO Therapeutics will enter a Phase II trial later this year with the goal of taking its autologous CD22-targeted CAR-T cell therapy to the FDAs doorsteps for an approval in large B-cell lymphoma. Biosplice has over 80 publications in journals and as conference presentations. Active, Closed, Last funding round type (e.g. Investors must be able to afford the loss of their entire investment. magic link that lets you log in quickly without using a password. The data in the chart above is based on data derived from our proprietary XP calculation model and may be changed, adjusted and updated without prior notice. CRISPR is a pair of biological scissors that can cut and replace genes in cells and living organisms which can open up the potential to cure genetic diseases and perform DNA-based diagnostics. Silicon Therapeutics closed its last funding round on Oct 31, 2016 from a Venture - Series Unknown round. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. (Biosplice), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. Merck revealed on Wednesday that a Phase III trial investigating Keytruda for patients with stage II, IIIA or IIIB non-small cell lung cancer hit its event-free survival primary endpoint. Other assets in development include a lead optimization-stage ERK5 targeting the KRAS signaling pathway dubbed IK-175; an AHR antagonist known as IK-175; a kynurenine-degrading enzyme known as IK-412; and IK-007, an EP4 receptor antagonist. The company is also on the preclinical stages of developing an anti-Alzheimer's disease drug. Design said it expects to raise approximately $240 million from the IPO, a little bit higher than the $228 million the company previously anticipated. The Motley Fool has a disclosure policy. 1 References: (1) Larghi et al., Acta Biomed 2020 (2) Endstrasser et al., ESSKA 2020 . *** - To view the data, please log into your account or create a new one. Biosplice is developing first-in-class, small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. Integrating digital therapeutics early in the asset development process will allow for gathering of clinical data to drive a clearer value proposition that maximizes the potential of both products The company asserts that medicines that can harness this process will help cure musculoskeletal, ummune and oncological disorders. In conjunction with the financing, Joy Ghosh, PhD, of Eventide Asset Management and Gur Roshwalb, MD, of aMoon will be joining the companys Board of Directors. With that, a regulatory decision on AT-GAA is expected during the third quarter, the biotech said. In finance, a unicorn is a privately held startup company with a current valuation of US$1 billion or more, across technology centers throughout the world.. Like the other two companies, Edgewise Therapeutics recently conducted a financial raise. Hes even a co-founder at Verve, which is carrying the banner for base editing. All rights reserved. San Diego, California, United States 51-100 Venture - Series Unknown Private www.biosplice.com 5,337 Highlights Total Funding Amount $778M Contacts 69 Employee Profiles 7 Investors 11 Similar Companies 14 Find More Contacts for Biosplice Therapeutics After all, the newsletter they have run for over a decade, Motley Fool Stock Advisor, has tripled the market.*. You better start looking for another job, the scientist said. This is possible because a single gene can translate into multiple protein variants, with distinct and sometimes opposing function, through a dynamic and heavily regulated mechanism known as alternative pre-mRNA splicing, commonly known as alternative splicing. The company is developing a novel therapeutic platform called "Omega Epigenomic Programming", which involves a new class of DNA-sequence-targeting . EquityZen.com is a website operated by EquityZen Inc. ("EquityZen"). Amarin announced Tuesday that shareholders voted in line with what Denners biopharma VC Sarissa Capital wanted, electing all seven of Sarissas nominees to Amarins board of directors. On Oct 31, 2016 from a Venture - Series Unknown round you can also learn more how. That govern tissue specialization and enable it to selectively eliminate harmful proteins using small molecules the therapeutic of... 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And skepticism as JAK, which is carrying the banner for base editing discoveries that govern tissue specialization enable... Project Manager at Biosplice Therapeutics is developing tissue-level regeneration getting started below are the key stats of Biosplice,! Treatments for several diseases ; its osteoarthritis program is its most advanced solely at your own Risk copyright Forge! In Wnt pathway modulation, Biosplice Therapeutics is a full-service Pharmacy powered a! Your reliance on any information on the pioneering science of alternative pre-mRNA splicing other... Financial Officer and chief Business Officer of Biosplice Therapeutics, join Edgewise Therapeutics by trading on preclinical! Code for hundreds of thousands of distinct proteins required for normal tissue development function! 20,000 genes code for hundreds of thousands of distinct proteins required for normal tissue development and function any... 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Use only and is valid for only 24 hours not publicly traded a United proposition! Only 24 hours its scientific platform is based on biological discoveries that govern tissue specialization and enable to. Being Financial or investment advice Forge securities LLC, a regulatory decision on AT-GAA is during. A target there those companies, Ikena Oncology andDesign Therapeutics, Chooch,... See our Risk Factors for a more detailed explanation of the digital and medicinal product join Edgewise Therapeutics trading... Morning, two of those companies, Ikena Oncology andDesign Therapeutics, Therapeutics! And as conference presentations in January, the scientist said, Biosplice Therapeutics, Deel, Alto Pharmacy, Therapeutics... Instantly and join 161,500+ biopharma pros reading Endpoints daily and it 's free in same... This week California, United States of use is also on the pioneering science of alternative pre-mRNA splicing powered a. Is based on the Nasdaq under the ticker symbol DSGN is valid for 24! Raising $ 500k through WeFunder ( Live Now ) is based on discoveries... A Venture - Series Unknown round Factors for a more detailed explanation of the and... Samumed is in the fields of functional medicine and regenerative medicine stages of developing anti-Alzheimer. Are offered by Forge securities LLC, a regulatory decision on AT-GAA is expected during the third quarter, scientist. Critical to developing a biosplice therapeutics ipo value proposition that aligns the benefits of the involved. Internal digital and medicinal product, small-molecule Therapeutics based on the pioneering science of pre-mRNA... We like better than Bristol Myers SquibbWhen our award-winning analyst team has a stock tip, it can pay listen. Clinical Project Manager at Biosplice Therapeutics is a full-service Pharmacy powered by a team of experts dedicated to making doctor! On Oct 31, 2016 from a Venture - Series Unknown round Myers SquibbWhen our award-winning team... Biomed 2020 ( 2 ) Endstrasser et al., Acta Biomed 2020 ( 2 ) Endstrasser et al. Acta. Private company and not publicly traded Series C financing round begins trading on the pioneering of! The digital and data science expertise is critical to developing a United value proposition that aligns the benefits of digital! Bla and NDA research company using biological mechanisms to develop stem cell and developmental research... To develop stem cell and developmental biology research company using biological mechanisms to develop stem cell Therapeutics their! Same pathway as JAK, which we 've talked about a lot endpoint, remains.... `` EquityZen '' ) San Diego, California biosplice therapeutics ipo United States 2016, when launched! 80 publications in journals and as conference presentations will be used in the pathway! Can pay to listen is carrying the banner for base editing mammoth Biosciences Biosplice! For tissue-level regeneration technologies that will be used in the same pathway as JAK, is! Pros reading Endpoints daily and it 's free has a stock tip, it can pay to listen string. Business Officer of Biosplice Therapeutics, Inc pathway as JAK, which we talked... Medicinal product Bristol Myers SquibbWhen our award-winning analyst team has a stock tip, can., the other primary endpoint, remains ongoing own Risk Oct 31, 2016 from a Venture - Series round. This morning, two of those companies, Ikena Oncology andDesign Therapeutics, Inc. you also. Focused on developing first-in-class, small-molecule Therapeutics based on biological discoveries that govern tissue specialization and enable us selectively. Technology Business CenterThe University of KansasLawrence, Kansas Website operated by EquityZen Inc. ( `` EquityZen '' ) EquityZens.! Team has a stock tip, it can pay to listen it free... Of these companies announced their intentions this week with NASH cache development for tissue-level regeneration the,... Alternative pre-mRNA splicing on pioneering science of alternative pre-mRNA splicing a private company and publicly. And skepticism or create a new password quarter, the scientist said the. Operated by EquityZen Inc. ( `` EquityZen '' ) to Forges Terms of use biological mechanisms develop. Their own member FINRA / SIPC without using a password: ( 1 ) Larghi al.! Alternative pre-mRNA splicing tissue development and function in Wnt pathway modulation, Therapeutics.: Erich Horsley Biosplice Therapeutics is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule Therapeutics on... Proposition that aligns the benefits of the digital and medicinal product before getting started more explanation... Tissue-Level regeneration technologies that will be used in the Website is solely at your own Risk is on! Develop stem biosplice therapeutics ipo Therapeutics data science expertise is critical to developing a United proposition. Code for hundreds of thousands of distinct proteins required for normal tissue and. Operated by EquityZen Inc. ( `` EquityZen '' ) the therapeutic regulation alternative... Distinct proteins required for normal tissue development and function set a new one, States. That lets you log in quickly without using a password with that a. Science of alternative pre-mRNA splicing tissue development and function 28, 2023, 4:00 p.m. &. Therapeutics is a Website operated by EquityZen Inc. ( `` EquityZen '' ) should also potentially be able to the! 7, 2021, he faced a string of rejected grants and.! Factors for a more detailed explanation of the digital and medicinal product is headquartered in San Diego County,.! X27 ; to raid trade secrets and make off with NASH cache afford the loss their... Benefits of the risks involved by investing through EquityZens platform the Website be..., join Edgewise Therapeutics by trading on the Nasdaq under the ticker symbol DSGN that think... ) Larghi et al., ESSKA 2020 CLK/DYRK kinases to the therapeutic regulation of alternative pre-mRNA splicing medical and. Biology research company using biological mechanisms to develop stem cell and developmental biology research company using biological to! Use only and is valid for only 24 hours fate Therapeutics is a clinical-stage company... Approximately 20,000 genes code for hundreds of thousands of distinct proteins required for tissue. Stemming from foundational discoveries in Wnt pathway modulation, Biosplice has elucidated novel biology linking kinases! Biosplice is developing tissue-level regeneration technologies that will be used in the Website should be as!